Product Details

Pregabalin was originally FDA approved in 2004 as an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Pregabalin also affects chemicals in the brain that send pain signals across the nervous system.

Pregabalin is used to treat pain caused by fibromyalgia, or nerve pain in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia), or spinal cord injury.

Pregabalin is also used with other medications to treat partial-onset seizures in adults and children aged at least 1 month.

How Pregabalin (Lyrica) works

Pregabalin (Lyrica) is a gamma-aminobutyric acid (GABA) analog, which decreases activity at the nerve endings to relieve pain and also can prevent seizures.

What is Pregabalin (Lyrica) used for?

Nerve pain, from diabetes, shingles, or spinal cord injury
Fibromyalgia
Seizures

Typical dosing for Pregabalin (Lyrica)

The dose of Pregabalin (Lyrica) is different for different indications. The typical starting dose for adults and children weighing more than 30 kg is 150 mg/day taken as 2 or 3 divided doses. The dose for children that weigh less than 30 kg depends on their weight. The maximum daily dose for each indication is as follows:

Diabetic Nerve Pain: 300 mg
Post-herpetic neuralgia: 600 mg
Fibromyalgia: 450 mg
Nerve pain from spinal cord injury: 600 mg
Seizures: 600 mg or 14mg/kg for children <30 kg.

Frequently asked questions about Pregabalin (Lyrica)

What is the use of Pregabalin (Lyrica)?

This medication is used to treat certain types of seizures, painful nerve conditions and fibromyalgia (muscle pain and tenderness).

Is Pregabalin (Lyrica) illegal?

No. This medication is legal and obtained through a prescription from your healthcare provider. This is a schedule V medication.

Do you take Pregabalin (Lyrica) with food?

If you were prescribed the longer acting tablet, it is recommended to take it after the last meal of the evening. All other products can be taken with or without food.

Can I take Pregabalin (Lyrica) with diazepam?

Do not take these two medications together without proper medical advice from your healthcare provider because this can be harmful to you.

Is Pregabalin (Lyrica) a benzodiazepine?

No, Pregabalin (Lyrica) is not a benzodiazepine. It belongs to another drug class of medications called anticonvulsants or GABA analogs.

Is Pregabalin (Lyrica) safe during pregnancy?

There aren’t enough studies to say whether taking Pregabalin (Lyrica) during pregnancy is safe for your baby. There is a North American Antiepileptic Drug (NAAED) Pregnancy Registry to monitor the safety of anti-seizure medications during pregnancy. If you are currently pregnant and taking Pregabalin (Lyrica), it is encouraged that you enroll in the registry to help researchers learn more about the risks.